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KMID : 1164220150270010023
Journal of Korean Society for Radiotherapeutic Technology
2015 Volume.27 No. 1 p.23 ~ p.30
Respiratory signal analysis of liver cancer patients with respiratory-gated radiation therapy
Kang Dong-Im

Jung Sang-Hoon
Kim Chul-Jong
Park Hee-Chul
Choi Byeong-Ki
Abstract
Purpose : External markers respiratory movement measuring device (RPM; Real-time Position Management, Varian Medical System, USA) Liver Cancer Radiation Therapy Respiratory gated with respiratory signal with irradiation time and the actual research by analyzing the respiratory phase with the breathing motion measurement device respiratory tuning evaluate the accuracy of radiation therapy.

Materials and Methods : May-September 2014 Novalis Tx. (Varian Medical System, USA) and liver cancer radiotherapy using respiratory gated RPM (Duty Cycle 20%, Gating window 40% ~ 60%) of 16 patients who underwent total when recording the analyzed respiratory movement. After the breathing motion of the external markers recorded on the RPM was reconstructed by breathing through the acts phase analysis, for Beam-on Time and Duty Cycle recorded by using the reconstructed phase breathing breathing with RPM gated the prediction accuracy of the radiation treatment analysis and analyzed the correlation between prediction accuracy and Duty Cycle in accordance with the reproducibility of the respiratory movement.

Results : Treatment of 16 patients with respiratory cycle during the actual treatment plan was analyzed with an average
difference -0.03 seconds (range -0.50 seconds to 0.09 seconds) could not be confirmed statistically significant difference
between the two breathing (p = 0.472). The average respiratory period when treatment is 4.02 sec (¡¾ 0.71 sec), the average value of the respiratory cycle of the treatment was characterized by a standard deviation 7.43% (range 2.57 to 19.20%). Duty Cycle is that the actual average 16.05% (range 13.78 to 17.41%), average 56.05 got through the acts of the show and then analyzed% (range 39.23 to 75.10%) is planned in respiratory research phase (40% to 60%) in was confirmed. The investigation on the correlation between the ratio Duty Cycle and planned respiratory phase and the standard deviation of the respiratory cycle was analyzed in each -0.156 (p = 0.282) and -0.385 (p = 0.070).

Conclusion : This study is to analyze the acts after the breathing motion of the external markers recorded during the actual treatment was confirmed in a reproducible ratios of actual treatment of breathing motion during treatment, and Duty Cycle, planned respiratory gated window. Minimizing an error of the treatment plan using 4DCT and enhance the respiratory training and respiratory signal monitoring for effective treatment it is determined to be necessary.
KEYWORD
Respiratory-gated radiotherapy, Gating window, Duty cycle, RPM
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